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The College was founded in 1425/1426 H. The Institute of Health for Girls provided a two-year academic plus half year training program to award the diploma certificate.
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The institute upgraded into the College of Health Sciences in the academic year 1428/1429 AH. The system of study was three years academic and a half year of internship which granted a middle university degree.
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The College of Health Sciences for Girls joined the King Saud University in 1428 AH. The program duration got extended to four years of academic and one-year training in order to grant a bachelor's degree.
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On the commencement of Shaqra University, the college came under its authority in 1430 AH with the operation of the girls' section only.
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The Department of Clinical Laboratory Sciences was inaugurated in the College with the induction of male students in 1431 H.
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The Department of Physical Therapy and Nursing got started for boys in the year 1433 H.